Deep knowledge AI agents for scientific discovery

Denario

An AI multi-agent system that acts as a scientific research assistant — generating ideas, checking the literature, developing research plans, writing and executing code, making plots, and drafting and reviewing scientific papers.

Install in seconds: pip install denario-mcp

A modular research pipeline

Each module handles a specific task — or chain them together for an end-to-end scientific analysis.

Idea

Generates research ideas through iterative refinement — an “idea maker” and an “idea hater” critique and improve each concept.

Literature

Validates novelty by classifying ideas as new or not new and retrieving relevant papers through semantic search.

Planning & Control

Deep research orchestration via the Cmbagent backend, enabling end-to-end analysis without human intervention.

Writing

A multi-agent workflow that produces complete scientific papers with methods, results, and supporting materials.

Execution

Writes and runs code, makes plots, and turns a research plan into reproducible results.

GUI & MCP

Drive Denario from a friendly app, or straight from Claude through the hosted MCP server.

Run it from Claude, securely

Denario is available as a hosted MCP server. Install the lightweight client, create an API key, and the research tools appear inside Claude. The heavy pipeline runs on our infrastructure; your project files are created on your own machine.

  1. 1

    Create an API key

    Sign in and generate a key on the dashboard.

  2. 2

    Install the client

    pip install denario-mcp

  3. 3

    Add to Claude

    Paste the MCP config with your key + server URL.

  4. 4

    Ask Claude

    Run denario_setup, then denario_idea.

Proven across disciplines

AstrophysicsBiologyBiophysicsBiomedical informaticsChemistryMaterial scienceMathematical physicsMedicineNeurosciencePlanetary science

A Denario-generated paper was accepted for publication at the Open Conference of AI Agents for Science 2025 — the first open conference with AI as primary authors.